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The new research, which was conducted with Schistosoma maintained in laboratory conditions, shows that an oxadiazole compound was effective in inhibiting a crucial worm enzyme, called thioredoxin glutathione reductase (TGR)

In addition, with the growing insights into the production and utilization of one-carbon units in cancer cells, multiple therapeutic strategies have been proposed, including nutrient therapy and targeting enzymes in one-carbon metabolism pathways

KYNA can confer protection against excitotoxicity via glutamatergic antagonism, yet excessive levels may simultaneously impair cholinergic signalling through 7nAChRs, contributing to mood and cognitive dysfunction