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Indeed, antiangiogenic drugs (AADs) by blocking tumor-derived factors demonstrate clinical benefits in human cancer patients 3,5

Citation on PubMed Langner C, Denk H

Furthermore, the degree of senescence before kidney transplantation is capable of predicting the patients outcome regarding graft success [89], indicating that targeting senescent cells may be an efficient therapeutic strategy in renal diseases, and various studies have reported improved renal function and attenuated kidney fibrosis following decreased senescent cells

Samantha Hocking: Has received research grants from Novo Nordisk, The Diabetes Australia Research Trust/Program and The National Health and Medical Research Council of Australia