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This selectivity is particularly important for individuals seeking pure fat reduction rather than body recomposition, those who do not want muscle hypertrophy for aesthetic or functional reasons, athletes in weight-class sports who need fat loss without muscle gain, individuals with contraindications to growth-promoting interventions, and those concerned about cell proliferation effects

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However, CYP2E1-driven metabolism generates substantially more reactive oxygen species per unit of ethanol oxidized than the ADH pathway