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Immediate effect (day 3): Whereas the controls exhibited an increasing disappearance of arcade vessels, particularly at the dorsal side of the colon (Figures 9, 13 and 14), after BPC 157 bath treatment the arcade vessels vigorously reappeared together with interconnected collaterals between arcades, in particular, quickly rescuing blood flow (a finding especially seen at the dorsal side of the colon) (Figures 18, 21 and 22)

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Melasma is a specific hormonal and UV-triggered form of hyperpigmentation that appears symmetrically on the face

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