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Unfortunately, the pharmacokinetics of the hemin in that trial were insufficient to conclusively test whether countering oxidative stress can restore normal ENS function and gastric emptying ( Potential Pharmacological Promotion of Neuronal Cell Differentiation As in other tissues, there is a dynamic balance in the enteric nervous system between cell loss by apoptosis, phagocytosis of dead cells by resident macrophages, and restoration of new cells from stem cells

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bHLH11 linked with 6-(2-methoxy-Z-vinyl)-7-methyl-pyranocoumarin and Glutathione, cgs1 linked with (7R)-(+)-Lyoniresinol 9-glucoside and glutathione in the co-expression network of DEGs and DEMs

(ii) BSO sensitized BTC cells to cisplatin through GSH depletion and downregulation of antiapoptotic proteins (Mcl-1, Bcl-2 and Bcl-xL)