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Weishaupt JH, Bartels C, Plking E et al (2006) Reduced oxidative damage in ALS by high-dose enteral melatonin treatment

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Abbreviations -SMA: alpha-smooth muscle actin ARG1: arginase-1 ASAL: arginigosuccinate lyase ASS: arginigosuccinate synthetase CD-HFD: choline-deficient high-fat diet CPS1: carbamoyl Phosphate Synthetase I FXR: Farnesoid X receptor GAB: glutaminase B GAC: glutaminase C GLS: glutaminase GLUD1: glutamate dehydrogenase 1 GPR91: cognate G protein-coupled receptor 91 GS: glutamine synthetase HCC: hepatocellular carcinoma HSC: hepatic stellate cells KGA: kidney-type glutaminase LGA: liver-type glutaminase LOLA: L-ornithine L-aspartate MCD: choline-deficient diet MCDD: methionine diet and choline-deficient diet MF: myofibroblasts NAFLD: non-alcoholic fatty liver disease NASH: non-alcoholic steatohepatitis OP: ornithine phenylacetate OCT: ornithine transcarbamoylase ROS: reactive oxygen species T2DM: type 2 diabetes mellitus TCA: tricarboxylic acid cycle VLDL: very low-density lipoprotein Declarations Funding This project was funded in part by the Spanish Ministry of Economy, Innovation and Competition, Instituto de Salud Carlos III (PI19/00589, PI19/01404, PI16/01842, PI17/00535 and GLD19/00100)

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