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The therapeutic effects of probiotics are multifactorial and exhibit substantial interindividual variability, influenced by the composition and metabolic activity of the hosts resident gut microbiota, the specific probiotic strain or strain combination employed, and the precise site of action within the GI tract (143)

doi: 10.1016/S0891-5849(02)01325-4 18 BloxhamDP

Berberis lycium which is rich in berberine has also been studied for its various cytotoxicity role on cancer cells, the compounds such as oxy berberine and -sitosterol effectively inhibit cell proliferation and hence used in anticancer drug discovery (Anwar et al., 2020)

Blacklow, S