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One trial found that both pregabalin and duloxetine improved patient-reported CIPN symptoms, with 150 mg of pregabalin performing better than 60 mg of duloxetine (Salehifar 2020)

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For instance, in the case of advanced/metastatic non-small cell lung cancer (NSCLC) with METex14, GEOMETRY mono-1, a multicenter, open-label, multicohort phase 2 trial, demonstrated that capmatinib was highly effective against tumors in patients with advanced or metastatic NSCLC at stages IIIB and IV, particularly those with METex14 or MET amplification, especially in settings without prior treatment [27]