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The synthesis of methionine primarily occurs through a pathway known as the transmethylation cycle or methionine salvage pathway

[DOI] [PMC free article] [PubMed] [Google Scholar] Viger-Gravel J., Schantz A., Pinon A.C., Rossini A.J., Schantz S., Emsley L

The presence of Auer rods (linear, myeloperoxidase-positive cytoplasmic inclusions) on a peripheral blood smear is pathognomonic for acute myelogenous leukemia

While tightly regulated MLCK and ROCK signalling supports normal epithelial transport and barrier modulation, excessive or sustained activation of these pathways contributes to pathological intestinal barrier dysfunction observed in inflammatory and infectious conditions (Xiong et al., 2026)