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We show that replacing the R140, N141, L142 and W145 residues with alanine or deleting residues 129148 of the disordered linker region of STX7 decreased binding to Munc13-4 in TR-FRET assays (Fig

1a), with the incidence varying between 40% and 85%, depending on the etiology 6,7,8

Biochim Biophys Acta 1830:32893303

In general, practitioners working with patients with mold and/or mycotoxin exposure focus on three key clinical areas: Addressing Mycotoxin Exposure Supporting the Foundations of Health Judicious Use of Supplements and/or Pharmaceuticals Address Mycotoxin Exposure First-Line Remediation/Defense: Removal/Avoidance of the Offending Agent The first line of defense against mycotoxin exposure as with any toxin or toxicant is identification and remediation of the source of exposure with the goal of preventive exposure strategies going forward