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It plays a crucial role in safeguarding cells from damage caused by harmful free radicals

Glutamate can contribute to the synthesis of glutathione through the activity of different enzymes, such as GCL

The response to GHRP2 in adults also suggests that rapid recrudescence of GHRH neuronal elements may be evoked by the ghrelin analog

Of particular importance are the colonic microbial metaboliteslow-molecular-weight phenolic derivatives generated via gut microbiotawhich have recently attracted attention for their potential role in modulating inflammation ( Moreover, considerable interindividual variability in EC metabolism exists, predominantly driven by differences in gut microbiota composition and host enzymatic profiles ( To bridge these critical knowledge gaps, this review systematically explores the anti-inflammatory mechanisms of EC, emphasizing the interplay between its structural properties, metabolic fate, and the bioactivities of its microbial metabolites