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COPD COPD is a heterogeneous lung disease characterized by chronic respiratory symptoms caused by bronchitis, bronchiolitis, and/or emphysema

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This immunological shift was mechanistically associated with inhibition of NF-B signaling and activation of PPAR, pathways well recognized for their opposing roles in inflammation and metabolic regulation ( 2 D 3 demonstrated modest reductions in hepatic mRNA expression of the pro-inflammatory cytokines TNF- and IL-6