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As mentioned earlier, the transition into ketosis can cause a cluster of keto diet side effects including fatigue, headache, irritability, nausea, and poor concentration

doi: 10.1016/j.cpcardiol.2018.06.005 2 al-WaizM.MikovM.MitchellSCSmithR

In clinical use, children with extensive thermal burns who were treated with IGF-I in combination with IGFBP-3, presented a reduction in serum levels of IL-1, TNF-, C-reactive protein, 1-acid glycoprotein, and complement C-3[299]