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Cagrilintide binds to amylin receptorsheterodimeric complexes of the calcitonin receptor (CTR) with receptor activity-modifying proteins (RAMP1 or RAMP3)

As to the pi class, GSTP1-1 point mutations in both exon 5 (codon 105) and exon 6 (codon 114) were observed and shown to have an impact on the enzymatic activity 32

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Iron elevation and adipose tissue remodeling in the epididymal depot of a mouse model of polygenic obesity