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Methylene blue side effects from intravenous treatment are rare and typically under high dosages but include nausea, discoloration of urine, arm or leg pain, change in taste, increased sweating, and feeling hot and cold

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Table 3 Linear mixed model fixed effects (Type-III Test)

Up-regulation of the manganese transporter SLC30A10 by hypoxia-inducible factors defines a homeostatic response to manganese toxicity