melanotic hyperpigmentation Pigmented macule on the mandibular gingiva (a, case 1), affecting the Pigmented Lesions of the Oral
Pigmented Lesions of the Oral Cavity Oral and Maxillofacial Surgery Clinics What Caused These Multiple Hyperpigmented Macules of the Mouth? Smokers melanosis . Oral pigmentation seen in heavy smokers . Investigations have shown ability of melanin to bind to noxious substances. . Exposure to polycyclic amines ( Nicotine & benzpyrene) has shown HIVAssociated Oral Mucosal Melanin Hyperpigmentation: A Clinical Study in a South African Population Sample Chandran 2016 AIDS Research and Treatment Wiley Online Library
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