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This will provide evidence to support clinical trials targeting ferroptosis and ultimately enable a full pipeline from basic mechanisms to translational tools and clinical application, ensuring that ferroptosis-based therapies progress from laboratory research to patient care

It is conceivable that genetic influences may be reflected in an endophenotype (hidden phenotype) of bipolar disorder characterized by abnormal circadian and hormonal rhythms, responses to medications, and specific gray- and white-matter changes (42, 6870)

After incubating at 37 C, 5% CO 2 for 7296 h, cell growth curve is obtained by analyzing cell confluence per well

Other transcription factors, such as Foxo1, NF-B, and cAMP-responsive element binding protein, are also involved in the regulation of transcription of GRKs (GRK2, GRK5, GRK6) [141,142,143]