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So far, it is hypothesized that (1) on-line benefits to stimulation might be the result of directly modulating Purkinje neuron activity, whereas off-line benefits may be the result from long-lasting changes to the activity of Golgi cells [267, 268], and (2) severe cerebellar atrophy with a major loss of neurons above a threshold is unlikely to respond well to non-invasive stimulation

It is studied for its ability to promote tissue repair, angiogenesis, and cellular healing across multiple organ systems, including muscle, tendon, nerve, and gastrointestinal tissue

Transdermal bioavailability is estimated at less than 5% for unformulated aqueous solutions

This makes it an attractive option for those looking to fade post-inflammatory hyperpigmentation or melasma