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Neither tesamorelin nor retatrutide has an established safety profile in pregnancy or breastfeeding

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Associations of Maternal Vitamin B12 Concentration in Pregnancy With the Risks of Preterm Birth and Low Birth Weight: A Systematic Review and Meta-Analysis of Individual Participant Data

In terms of AEs, the studies indicated minor complications (such as cutaneous edema and skin anesthesia) in 3.5% to 11% of cases, with major complications occurring in less than 2% of cases (one patient with second-degree skin burn and peritonitis due to a probable small-bowel injury, which required local skin care and 5 days of hospitalization with intravenous antibiotic therapy