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Figure 4 ALA significantly inhibits the expression of signaling proteins of ER stress following CSD In order to further investigate whether ALA would exert the hepatoprotective effects through modulating the activities of endoplasmic reticulum stress (ER stress) following CSD, the expressions of signaling proteins involved in the process of ER stress (such as ATF6, IRE1, and PERK) were quantitatively examined by the immunoblotting analysis

Mass spectrometry analysis utilized a heated electrospray ionization (HESI) source: spray voltage 3.5 kV, capillary temperature 275 C, sheath gas 55 arbitrary units, auxiliary gas 15 arbitrary units, sweep gas 3 arbitrary units, heater temperature 450 C, and an RF level of 50

But adverse event reports for unapproved products were not made publicly available