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Description

the number of freeze-thaw cycles

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By breaking down intracellular components, autophagy sustains bioenergetic balance and promotes cell survival until favorable conditions are restored ( Autophagy is a highly conserved catabolic process involving four key steps: initiation, autophagosome formation and maturation, fusion with lysosomes, and degradation of autophagic cargo

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Activation of mTOR signal promotes the immunosuppressive microglial formation by regulating the activity of the transcription factors STAT3 and NF-B

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Guasti L et al

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