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Oct 2015;29(10):1106-11

AMPK is a critical bioenergy sensor, and the functional role of AMPK has been extensively studied in lipid metabolism (fatty acids, mitochondria, and cholesterol), glucose metabolism, protein synthesis, inflammation mitigation, mitochondrial biogenesis, apoptosis, and many other aspects [21]

doi: 10.1186/1475-2891-11-7

Behavioral therapies advocate for a consistent sleepwake schedule, morning exposure to bright light, and cognitive behavioral therapy for insomnia, albeit the latter which is seldom available for cirrhosis patients