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CHAC1-mediated GSH degradation reduces S-glutathionylation of ARF6 at cysteine 90, thereby inactivating ARF6 and enhancing ferroptotic cell death ( Similarly, CHAC1 is upregulated in various kidney disease models ( CHAC1 upregulation was induced by cysteine and methionine deprivation, treatment with erastin and exposure to tunicamycin

Acute Myelogenous Leukemia (AML) Mesenchymal Stromal Cell (MSC) Have Distinct Protein Expression Patterns Compared to Normal MSC

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Glucosinolates are synthesized from various protein and non-protein amino acids, cysteine and glucose in a manner very similar to the biosynthesis of cyanogenic glucosides except for the addition of sulfur from cysteine