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Huang J.-T., and Lajtha A., 1978

Prior to the synthesis and isolation of these peptides, research into accelerated tissue healing and recovery relied largely on broad growth factors and nonspecific interventions

During this process, molecules like intercellular cell adhesion molecule-1 and vascular cell adhesion molecule-1 increase on inflamed endothelial cells surfaces, and can be taken in by cell-mediated transocytosis (Wang et al., 2022)

The dasatinib-plus- quercetin combination cleared senescent cells in a first-in-human trial, and a small feasibility trial is testing it in Alzheimers, though the brain evidence is early