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This multi-step process makes NR a "precursor" rather than a direct form of NAD+

30,32 A retrospective matched case-control study of 324 patients who underwent ACL reconstruction with meniscus repair (PRP vs control age: 91.6 11.2 vs 92.4 10.6) showed no significant difference in IKDC scores nor in the timing of return to activity nor postoperative complications among the intraoperative PRP injection group and the control group after 2 years 33 In addition, Bailey et al

However, this popularity has often outpaced the actual clinical evidence, creating a significant gap between laboratory enthusiasm and evidence-based claims about human application

doi: 10.1007/s11420-006-9029-9