For prescription topical formulations used consistently, initial improvements in texture, hydration, and radiance typically appear at 2 to 4 weeks, meaningful visible changes to firmness and fine lines at 4 to 8 weeks, maximum early results at 8 to 12 weeks, and full cumulative benefit at 3 to 6 months of consistent daily use
What I will say is if youre going to experiment with intranasal delivery, then do the following: Start at the lower end of the dosing range Assess tolerability Track your results systematically so you can actually evaluate whether its doing anything for you BPC-157 Nasal Spray Side Effects and Safety BPC-157 is not approved by the FDA or EMA for any medical use, and it is listed by WADA as a prohibited substance under peptide hormones and growth factors
Sermorelin can be compounded for growth hormone support as an alternative to banned secretagogues

Anti-aging and longevity peptides Epithalon: Standard shelf life: 28-30 days refrigerated Maximum: 30-35 days Short peptide sequence, stable Thymosin Alpha-1: Standard shelf life: 28-30 days refrigerated Maximum: 45 days (pharmaceutical grade) Relatively stable peptide Semax and Selank: Standard shelf life: 28-30 days refrigerated Maximum: 30-35 days Short peptides, stable Sexual health peptides PT-141 (Bremelanotide): Standard shelf life: 28-30 days refrigerated Maximum: 45 days (pharmaceutical Vyleesi) Stable peptide Melanotan II: Standard shelf life: 28-30 days refrigerated Maximum: 35-40 days Relatively stable Copper peptides (GHK-Cu) GHK-Cu injectable: Standard shelf life: 28-30 days refrigerated Maximum: 30 days (copper can catalyze oxidation) More sensitive than other peptides due to copper ion Special note: Copper peptides may show visible degradation (color change to greenish/blue) if stored too long