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On the other hand, the mutant was active on all tested diphenolic substrates (Fig

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Additionally, the detoxifying properties of AS-IV may indirectly reduce the risk of arrhythmia induced by these drugs, thus providing a promising strategy to improve the safety and efficacy of anti-tumor treatments

After the cells reached ~ 80% confluence under normal culture conditions, the medium was changed to glucose-free DMEM (Gibco) and the dish was placed in an anaerobic chamber (5% CO2, 95% N2) to induce OGD-related cell injury