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Therefore, these antioxidants represent a potential new target for chemotherapy treatments, especially the thioredoxin reductase (TrxR) protein, which can be targeted through its selenocysteine residue

Ohori F, Kitaura H, Ogawa S, Shen W-R, Qi J, Noguchi T, et al

Milk thistle may not suit people with certain plant allergies, alpha-lipoic acid may influence blood sugar, and excessive selenium intake can become harmful

24 Notably, ferritinophagyan NCOA4 (nuclear receptor coactivator 4)-mediated autophagic degradation of ferritin in the lysosomehas been shown to induce ferroptosis by releasing free iron from ferritin