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Matsuoka T, Oya N, Yokota H, Akazawa K, Yamada K, Narumoto J, et al

However, clinical trials with T4 gels at various concentrations (0.01, 0.02, 0.03, and 0.1%) in patients with pressure ulcers, venous leg ulcers, and epidermolysis bullosa showed no statistically significant difference in healing as compared to that of placebo, although some trends towards faster healing were noted at intermediate doses during early weeks [242,243]