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These covalent adducts that are formed by MG are collectively called advanced glycation end products (AGEs) (Rabbani and Thornalley, 2015)

Chen SD, Yang DI, Lin TK, Shaw FZ, Liou CW, Chuang YC (2011) Roles of oxidative stress, apoptosis, PGC-1 and mitochondrial biogenesis in cerebral ischemia

The compounds combination of a small peptide backbone with a coordinated copper ion gives it dual structural identity, both as a signaling peptide and as a copper-delivery vehicle, and that combination underlies much of its observed research activity

stomach pain increased salivation quick heavy breathing tachycardia 1) hypertension headache pale skin muscle fasciculations & weakness seizures Late inhibitory phase (including Muscle paralysis & Ganglionic blockade) (30 mins to an hour): bradycardia diarrhea dyspnea shallow breathing hypotension lethargy / coma severe muscle weakness & paralysis respiratory failure (paralysis of diaphragm) Pharmacokinetics: Nicotine is well absorbed through the skin Major drug Interactions: May alter the pharmacokinetics of certain concomitant medications, such as tricyclic antidepressants and theophylline