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Benz MR, Lee SH, Kellner L, Dhlemann C, Berweck S

78% were White,16% were Asian, 2.9% were Hispanic or Latino, 2.1% were Black or African American, and 80 mL/min following concomitant administration of ibuprofen (OAT3 inhibitor) 400 mg four times a day

Reuben A, Zhang J, Gittelman R, Chiou SH, Li J, Fujimoto J, Behrens C, Kheradmand F, Chow CW, Bernatchez C, Eterovic AK, Benzeno S, Vignali M, Wu X, Ye Y, Cascone T, Rerbst R, Swisher SG , Kadara H, Moran C, Zhang J, Scheet P, Vaporciyan A, Sepesi B, Gibbons D, Robins H, Hwu P, Heymach J, Sharma P, Allison J, Lee J, Davis M, Wistuba I, Futreal A, Zhang J

By stimulating collagen production in the skin, it strengthens the skin at a structural level, resulting in a more youthful appearance