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Post-Surgical Care: Patients who have undergone gastrointestinal surgeries, such as gastrectomies or ileal resections, may face challenges in absorbing B12 from food due to changes in the digestive process

The elevated cystine uptake observed in SCC47 might represent a compensatory mechanism to maintain sufficient glutathione levels and prevent oxidative stress-induced cell death, a vulnerability previously identified in cancer cells, though future validation on SLC7A11 gene expression in HNSCC is needed 50

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