l-glutathione cancer treatment Application of glutathione depletion in therapy: Enhanced ROS-based therapy, ferroptosis, and chemotherapy Role of Glutathione in Cancer:

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Despite the fact that BSO does not affect overall cellular PDI levels, we found that cells with selective PDI knockdown clearly manifest a markedly-reduced sensitivity to BSO-induced ferroptosis

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Briefly, reverse activity was measured in 1.5 ml 50 mM HEPES, pH 7.5, 100 mM KCl, containing 50 l proteoliposomes, 1 M CCCP, 0.2 M valinomycin, 100 M NADPH and in presence or absence of 6.7 g/ml alamethicin