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Besides, ursolic acid showed similar protective effects through LKB1/AMPK pathway activation, elevating GPX4 and SLC7A11 expression while enriching Firmicutes and suppressing Bacteroidota [173]

Inflammopharmacol 17(3):181190 Rasool M, Sabina EP (2008) Evaluation of the protective potential of spirulina fusiformis on lipid peroxidation and antioxidant status in adjuvant-induced arthritic mice

AIMS Mol Sci 3:196221

found that ALS patients with lumbar-onset symptoms exhibited more pronounced iron dyshomeostasis in the motor cortex compared to cervical-onset patients (348)