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It needs to become a nuanced dialogue about context, purity, and individual risk factors

REDEFINE 4 (Phase 3, Feb 2026 readout) Open-label vs tirzepatide

When looking at the percentage of participants that dropped out of the trial due to adverse effects, 2-6% of patients in the cagrilintide group discontinued treatment early while 7% of the participants receiving liraglutide discontinued treatment early, These findings were in comparison to only 3% of test subjects from the placebo group that discontinued treatment due to adverse events [1]

For a plain-language primer, see our overview of what BPC-157 is and how it is described in research