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This hypothesis suggests that there are reduced levels of key neurotransmitters, including serotonin, dopamine, and noradrenaline, within the brain that contribute to both the onset and persistence of depressive symptoms (51, 52)

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The pathways that regulate GSH production and recycling are extremely complex [Figure 1], and most research on this system has been conducted through association studies which can suggest local mechanisms but cannot fully capture the interactions in the system as a whole

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