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PMID: 14 WangRMurrayCSFowlerSJSimpsonADurringtonHJ

NINJ1 regulates ferroptosis via xCT antiporter interaction and CoA modulation

Its putative trafficking to mitochondria has emerged as an important player as shown in a cohort of patients with established MASH, which exhibited increased free cholesterol content and high expression of the steroidogenic acute regulatory protein (STARD1) compared to patients with simple steatosis [87]

Mol Ther 16(6):10561064 Alam M, Yadav RK, Minj E, Tiwari A, Mehan S (2020) Exploring molecular approaches in amyotrophic lateral sclerosis: drug targets from clinical and pre-clinical findings