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(2020) proposed the hypothesis of the relationship between iron utilization and fibroblast growth factor-23 (FGF23) production, a vital regulator of phosphate homeostasis

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In cultured microvascular endothelial cells, hepcidin significantly inhibits the expression of FPN1, TfR1 and DMT1, and reduce iron uptake and release by neurons (Du et al., 2015)