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L-carnitine emerged as one of the few dietary supplements showing significant efficacy in reducing fatigue in ME/CFS patients according to a systematic review, notwithstanding methodological limitations such as small sample size and potential selection bias [136]

Kauffman MEMMMK, Kauffman MEMMMK, Traore K, Zhu H, Trush MA, Jia Z, et al

Cancer drugs, genetic variation and the glutathione-S-transferase gene family

Beta-amyloid is also present inside neurons, and while soluble, it can likely enter neurons from the outside (Guo et al., 2013) and beta-amyloid (Guo et al., 2017