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Hexarelin has dual receptor activity u2014 it activates both GHS-R1a (for GH release) and CD36 (for cardiac signaling)

Beyond that, the evidence is per-compound plus the CagriSema (cag + sema) Phase 3 data as the closest human analog

Simultaneous imaging of axonal boutons and their partnering spines in the context of behavioral manipulation will provide abundant information to address this question