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Cross talk between brain innate immunity and serotonin signaling underlies depressive-like behavior induced by Alzheimers Amyloid- oligomers in mice

New skin formed during treatment can be more sensitive to sunlight

Paraxanthine has been shown to increase BDNF levels to a greater extend compared to caffeine in a preclinical study [10], which translated in increased cognitive performance in a clinical study investigating the ability to shift between tasks [34]

Avoid late-stage asset loss Earlier mechanistic insights into human DILI enable actionable rectification by redesigning promising molecules into safer variants