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Data represent the means standard error of the mean of the metabolites peak area, Students t -Test (1-tailed, homoscedastic), considering significant differences for p -values 0.05

Arterioscler Thromb Vasc Biol 39(7):1483-91 2019 PMC6594860 Barrett TJ, Distel E, Murphy AJ, Hu J, Garshick MS, Ogando Y, Liu J, Vaisar T, Heinecke JW, Berger JS, Goldberg IJ, Fisher EA

207,208 Several plant-derived bioactive compounds upregulate SIRT1 expression or enzymatic activity via diverse mechanisms, showing positive effects in MASLD-related studies