glutathione inhibitor bso DL-Buthionine-sulfoximine Frontiers | Preclinical investigations of

Frontiers Preclinical investigations of the efficacy of the glutaminase inhibitor CB 839 alone and in combinations in chronic lymphocytic leukemia The glutathione synthesis inhibitor buthionine sulfoximine synergistically enhanced melphalan activity against preclinical models of multiple myeloma Blood Cancer Journal Lowering glutathione level by buthionine sulfoximine enhances in vivo photodynamic therapy using chlorin e6 loaded nanoparticles ScienceDirect The relative ability of BSO and other glutamylcysteine synthetase inhibitors to both deplete glutathione and alter drug metabolizing enzyme activities ScienceDirect

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