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For researchers who have experience switching from tirzepatide to retatrutide or other peptide transitions , similar principles apply

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T.ElnagdyS.KaczmarekK.MatsoukasJ.et al (2021)

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Start: Begin at 0.25 mg (gradual) or 0.6 mg (advanced) weekly to settle tolerability [1] [4]

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That is the entire basis for the CagriSema combination therapy that has generated so much excitement in clinical trials

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