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doi: 10.1016/j.clnu.2021.02.005 31

J Crohns Colitis 11, 649670

Tuttolomondo et al., 2020)

Darber hinaus kann durch eine verstrkte Hochregulation der Poly-(Adenosindiphosphat-Ribose)-Polymerasen-Inhibitoren (PARPi) die Apoptose und Zellproliferation moduliert werden, was eine Tumorprogression hin zu einen aggressiveren Phnotypen mit Arzneimittelresistenz und Metastasierung bedingt wird [27, 29]