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proposed a vascular normalization theory in which a judicious intensity of anti-angiogenic therapy could result in an equilibrium between anti-angiogenic and pro-angiogenic signals within the TMEvascular normalization statusand enable efficient delivery of oxygen, drugs, and anti-cancer immune cells into the tumor, rather than inducing excessive destruction of vessels and intratumoral hypoxia 35,36

Front Cell Neurosci 15:695479 Wang L, Gao F, Chen Z (2025) Targeted peptide therapeutics for amyloid clearance

It is not known whether the components of Lipo-B (particularly vitamin B or amino acids in high doses) could affect a nursing infant, and therefore the safest course is to avoid such injections while breastfeeding