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The obtained table of quantified peptides was then imported into Perseus (v2.0.1.0) and filtered to contain only the peptides with reported MG-H1 modification on arginines

Since its discovery, the effectiveness of molecular hydrogen in various diseases, such as ischemiareperfusion injury 8 , IBD 9 , and hepatitis 10 has been reported

Consistently, increased ME1 and TXNRD1 expression was confirmed in intestinal tissues from metformin-treated mice, validating antioxidant remodeling in vivo (Supplementary Fig