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Typically, cells contain a spectrum of endogenous antioxidant enzymes, such as GSH, GPX, SOD, CAT, PRX, and Trx, which can directly scavenge dangerous ROS (hydroxyl radicals, peroxyl radicals, superoxides, and lipid peroxides) and maintain intracellular redox homeostasis [45, 46]

In the following sections, the various direct mechanisms of acrolein toxicity such as protein and DNA adduction, and indirect mechanisms including induction of oxidative, mitochondrial, and ER stress, are critically discussed with possible connection to affected organs and pathological conditions

By restoring optimal levels of this vital peptide, patients can achieve a more youthful, radiant appearance while supporting internal tissue regeneration

Griendling KK, Touyz RM, Zweier JL, Dikalov S, Chilian W, Chen YR, Harrison DG, Bhatnagar A, American Heart Association Council on Basic Cardiovascular Sciences