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In a disease as heterogeneous as ME/CFS, it is difficult to find a reproducible biomarker

Toll-free in the U.S.: 1-888-644-6226 Telecommunications relay service (TRS): 7-1-1 Website: Email: [email protected] (link sends email) PubMed A service of the National Library of Medicine, PubMed contains publication information and (in most cases) brief summaries of articles from scientific and medical journals

Studies have shown that thiamine deficiency, and the resulting cognitive function decline, are the underlying factors in some neurodegenerative diseases (Alzheimers disease, Parkinsons disease)

reported that high glucose treatment of human fetal neural progenitor cells (ReNcell VM) induces epigenetic modification to alter the DNA methylation pattern of neurodevelopment-associated genes 34