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In one prospective controlled trial, 100 patients at a single center in Italy who had experienced inadequate response to DMARD therapy were randomly assigned to open-label treatment with infliximab 5 mg/kg every 6 to 8 weeks, etanercept 25 mg twice-weekly or adalimumab 40 mg every other week

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10.1007/s00726-011-0915-1 [DOI] [PubMed] [Google Scholar] Garcia N, Santafe MM, Tomas M, Lanuza MA, Besalduch N, Tomas J (2010) Involvement of brain-derived neurotrophic factor (BDNF) in the functional elimination of synaptic contacts at polyinnervated neuromuscular synapses during development